Foxx could have been deadly had he taken care of himself. However, I take him at face value, but with modern equipment. But Foxx was helped by his home park. I think Pujols has already passed Foxx. We will need to see how Pujols declines. I don't consider 2010 a down year for Pujols at all. 2010 was a typical Pujols year with league leading 173 OPS+, which matches his OPS+ for his first 9 seasons. Granted, it was 26 pts off his career high. But Ruth's 1927 season was 30 OPS+ pts lower than his best season. I doubt people thought that Ruth had an off year in 1927. In 2011, Pujols fractured his wrist. Breaking a bone can have an impact on one's yearly stats. So I see why he had a down year. Even Babe Ruth in 1922 and 1925 had off seasons when he was injured(or suspended). I'm a bit concerned about Pujols' 2012 season. Perhaps he's truly in a decline now. I guess I'm in denial. However, any player can have an off-year. To me, the verdict will be out on Pujols' decline after the 2013 season. Pujols takes such good care of himself, that I don't see how he can decline at such an early age. If he is, then he'll have a tough time catching Gehrig. But I have a feeling that he's due for some more monster seasons, which'll allow him to pass Gehrig. That's my gut right now. Gehrig would be MUCH tougher to take down had he not had that unforunate disease. And FWIW, I give Pujols a huge clutch factor. Pujols' .330/.439/.607 in postseason play is monstrous over 321 PA. Of course, Gehrig was extremely clutch as well.
I wonder how big Gehrig and Foxx would have done today with serious weight training. I can't imagine how big they would have gotten. They were already pretty muscular guys, particularly when considering that they played 80 years ago when weight training was a joke.